Yoé Skincare, founded by Hazel Guo and driven by a mission to deliver true skin transformation for sensitive and autoimmune-prone complexions, has officially launched at Bloomingdale’s—both online and in select stores as of September 18, 2025. This expansion marks a breakthrough moment for the biotech-powered, science-first brand, trusting its rigorously crafted formulas to one of luxury’s most selective destinations.
Founder’s Vision, Biotech Innovation, and Clean Formulation
Born from Guo’s own journey with autoimmune-linked skin sensitivity, Yoé is based on precise biotechnology and a relentless commitment to gentle efficacy. Each formula uses advanced encapsulated actives—like ceramides, hyaluronic acid, EGF (epidermal growth factor), niacinamide, tranexamic acid, and red algae—to deliver visible results while remaining ultra-gentle, even for those with the most fragile skin barriers.
Yoé’s “clean without compromise” promise is backed by EWG Verification™, Leaping Bunny Certification, vegan status, and a strict no-fragrance policy. According to founder Guo, “With Yoé, we set out to create skincare that outperforms beyond the surface, combining biotech innovation with results-driven simplicity. Our partnership with Bloomingdale’s marks an important step in sharing that vision with a wider audience of discerning clients and experts”.
Ympossible Creams: Multi-Awarded and Clinically Proven
Central to the collection are the Ympossible Cream and Ympossible Cream Light, which, within a year, received the Oprah Daily Beauty O-ward, Cosmopolitan Holy Grail Award, and Women’s Health Beauty Award. Dermatologist-tested and hypoallergenic, these creams hydrate, support barrier repair, firm skin, and visibly improve lines, texture, tone, and redness—all in a single step.
Celebrity makeup artists and estheticians rely on Yoé creams as essential skin-prep for red carpets and major events, citing instant absorption, smoothing, and the ability to prime skin for makeup flawlessly. Even beauty editors and influencers laud their efficacy in unifying routines for busy, ingredient-savvy consumers.
SynerGenius® Complex: The Power of Biotechnology
At the heart of Yoé’s unique formulations is the proprietary SynerGenius® Complex, developed in collaboration with leading scientists, including an Italian Chief Scientist and a pharmacist. This delivery technology ensures each active—whether brightening, firming, hydrating, or calming—reaches optimal skin layers and releases evenly over time, supporting both immediate glow and lasting transformation.
Clean, Sustainable, and Eco-First
Yoé’s advanced science meets a planet-first ethos: all packaging is refillable and eco-friendly, and the brand donates through 1% for the Planet. This holistic approach is crucial as luxury consumers increasingly expect both high performance and deep ethical responsibility from beauty brands. In fact, Yoé is among the few brands actively building routines that streamline steps, minimize waste, and support sustainable living.
Bloomingdale’s: The Intersection of Innovation and Prestige
By joining Bloomingdale’s, Yoé has entered a retail sphere known for launching and elevating trailblazing brands. This partnership aligns Yoé’s award-winning, cruelty-free biotech approach with the broader movement of luxury retail toward clean, data-driven skin health and routine simplification.
Yoé’s arrival at Bloomingdale’s is also a reflection of the retailer’s commitment to featuring the most advanced and conscious brands during its bold fall 2025 campaign, connecting discerning shoppers to the very latest in skin science and sustainability.
Looking Forward: Raising the Bar for Skincare
With continued investment in innovation, expanded clinical testing, and forthcoming launches that leverage even smarter encapsulation and new actives, Yoé’s future is bright. The brand’s blend of scientific integrity and holistic philosophy continues to win the trust of consumers and professionals everywhere.
