Estée Lauder has taken a minority stake in 111SKIN, a luxury clinical skin care brand founded by a plastic surgeon, a strategic bet on the fast-growing intersection of medical expertise and prestige beauty. The Estée Lauder Companies has announced a minority investment in 111SKIN, a luxury clinical skin care brand founded by renowned plastic and reconstructive surgeon Dr. Yannis Alexandrides. Financial terms of the deal were not disclosed.

111SKIN distributes through luxury retail, e-commerce, and high-end spa channels, with partners including Harrods, Bluemercury, Nordstrom, Mandarin Oriental, and Aman. The brand’s direct-to-consumer business represents approximately 20% of sales, reflecting strong digital engagement with prestige consumers. North America accounts for approximately 40% of 2025 sales, with an established presence across China, the United Kingdom, Europe, and Asia Pacific.

“We are thrilled to be partnering with The Estée Lauder Companies and to unlock an exciting new chapter for 111SKIN,” Dr. Yannis and Eva…